A method of detecting gene mutation by mixing PCR-amplified mutant and wild-type DNA followed by denaturation and reannealing. The resultant products are resolved by gel electrophoresis, with single base substitutions detectable under optimal electrophoretic conditions and gel formulations. Large base pair mismatches may also be analyzed by using electron microscopy to visualize heteroduplex regions.
See also reference (FX) in Slovak
mismatch párovanie báz heteroduplexy nukleovej kyseliny
See also reference (FX) in English
Base Pair Mismatch Nucleic Acid Heteroduplexes
Links
(5) - ARTICLES
(2) - MeSH descriptor
(3) - CiBaMed
subject heading
Number of the records: 1
openseadragon
This site uses cookies to make them easier to browse. Learn more about
how we use cookies.
