A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
See also reference (FX) in Slovak
fragilita chromozómov nestabilita genómová
See also reference (FX) in English
Chromosome Fragility Genomic Instability
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(2) - MeSH descriptor
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openseadragon
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