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Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy

  1. TitleInfluence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity and patients with excellent tolerance of fluoropyrimidine-based chemotherapy
    Author infoZ. Kleibl ... [et al.]
    TitleVplyv variantov kódujúcich sekvencie génu dihydropyrimidín dehydrogenázy (DPYD) na vývoj toxicity spojenej s fluoropyrimidínom u pacientov s vysokým stupňom toxicity a u pacientov s výbornou toleranciou chemoterapie fluoropyrimidínom
    Co-authors Kleibl Zdeněk
    Fidlerová J.
    Kleiblová Petra
    Kormunda Stanislav
    Bílek M.
    Boušková K.
    Ševčík Jan
    Novotný Jan
    NoteBibliogr. odkazy. - Res. angl.
    Sign.C 720
    Source Neoplasma : journal of experimental and clinical oncology. - ISSN 0028-2685. - Bratislava : AEPress , 2009 . - Vol. 56, no. 4 (2009), s. 303-316  : ilustr. (aj fareb.), grafy, obr., tab.
    MeSH Subject fluorouracil : analógy a deriváty : toxicita : účinky nežiaduce
    pyrimidíny
    gény : účinky liekov
    analýza DNA, mutačná
    haplotypy
    farmakoterapia : účinky nežiaduce
    štúdia celogenómová asociačná
    Subj. Headings fluoropyrimidíny * 5-fluorouracil * gén dihydropyrimidín dehydrogenázy * varianty génu
    LanguageEnglish
    CountrySlovak Republic
    Document kindRozpis článkov z periodík
    DatabaseARTICLES
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