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proteín cytokínovej signalizácie 1, supresorový

  1. Record numberd000071222
    Date06.06.2025
    TypeM - MESH
    Topical termproteín cytokínovej signalizácie 1, supresorový
    Other termSlovak (Pseudonym) supresor cytokínovej signalizácie 1
    Slovak (Pseudonym) SOCS1 proteín
    UDCD12.644.360.024.374.500D12.776.157.057.249.500D12.776.476.024.437.500
    NoteA suppressor of cytokine signaling protein that consists of an N-terminal kinase-inhibitory region, a central SH2 DOMAIN, a characteristic C-terminal SOCS box (a 40-amino acid motif, which functions to recruit E3 UBIQUITIN-PROTEIN LIGASE COMPLEXES). SOCS1 functions as a negative regulator of CYTOKINES that signal through the JANUS KINASES-STAT 3 TRANSCRIPTION FACTOR (JAK/STAT3) pathway by inhibiting the activity of JANUS KINASES.
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