Number of the records: 1
rozmanitosť protilátok
Record number d000916 Date 06.06.2025 Type M - MESH Topical term rozmanitosť protilátok Other term English (Pseudonym) Germ Line Theory
Slovak (Pseudonym) teória zárodočnej línie
Slovak (Pseudonym) rôznorodosť protilátková
Slovak (Pseudonym) rôznorodosť protilátok
Slovak (Pseudonym) diverzita protilátok
Slovak (Pseudonym) diverzita protilátková
See also (Later heading) zmena génového usporiadania
UDC G05.365.036G12.500.199 Note The phenomenon of immense variability characteristic of ANTIBODIES. It enables the IMMUNE SYSTEM to react specifically against the essentially unlimited kinds of ANTIGENS it encounters. Antibody diversity is accounted for by three main theories: (1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; (2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and (3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of IMMUNOGLOBULIN VARIABLE REGION gene segments during the differentiation of the ANTIBODY-PRODUCING CELLS. subject heading
Number of the records: 1