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toxín diftérie

  1. Record numberd004167
    Date06.06.2025
    TypeM - MESH
    Topical termtoxín diftérie
    Other termEnglish (Pseudonym) Corynebacterium Diphtheriae Toxin
    Slovak (Pseudonym) toxín záškrtu
    Slovak (Pseudonym) toxín Corynebacterium diphtheriae
    See also(Later heading) Corynebacterium diphtheriae
    (Skutočné meno) jedy
    (Skutočné meno) toxoid difterický
    (Later heading) toxoid difterický
    UDCD08.811.913.400.725.115.220D23.946.123.305
    NoteAn ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.
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