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disulfiram
Record number d004221 Date 06.06.2025 Type M Topical term disulfiram Other term English (Pseudonym) Tetraethylthiuram Disulfide
See also (Skutočné meno) prípravky na odvykanie od alkoholu
(Skutočné meno) inhibítory acetaldehyddehydrogenázy
UDC D02.241.081.251.869.220.250D02.886.520.150.175D02.886.706.200.200 Note A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. 
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Number of the records: 1