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faktor XII

  1. Record numberd005174
    Date06.06.2025
    TypeM - MESH
    Topical termfaktor XII
    Other termEnglish (Pseudonym) Coagulation Factor XII
    English (Pseudonym) Hageman Factor
    Slovak (Pseudonym) faktor koagulačný XII
    Slovak (Pseudonym) Hagemanov faktor
    See also(Skutočné meno) koagulanciá
    (Skutočné meno) angioedém dedičný, typ III
    (Later heading) angioedém dedičný, typ III
    UDCD08.622.500D12.776.124.125.450D12.776.811.243.500D23.119.450
    NoteStable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.
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