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glukóza-6-fosfát izomeráza

  1. Record numberd005956
    Date06.06.2025
    TypeM
    Topical termglukóza-6-fosfát izomeráza
    Other termEnglish (Pseudonym) Glucosephosphate Isomerase
    English (Pseudonym) Phosphoglucose Isomerase
    English (Pseudonym) Phosphohexose Isomerase
    Slovak (Pseudonym) glukózafosfátizomeráza
    Slovak (Pseudonym) glukóza-6-fosfátizomeráza
    UDCD08.811.399.475.200.350
    NoteAn aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
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Number of the records: 1  

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