Number of the records: 1  

kernikterus

  1. Record numberd007647
    Date06.06.2025
    TypeM - MESH
    Topical termkernikterus
    Other termEnglish (Pseudonym) Bilirubin Encephalopathy
    English (Pseudonym) Hyperbilirubinemic Encephalopathy
    Slovak (Pseudonym) žltačka jadrová
    Slovak (Pseudonym) ikterus jadrový
    Slovak (Pseudonym) encefalopatia bilirubínová
    Slovak (Pseudonym) encefalopatia hyperbilirubinemická
    UDCC10.228.140.163.480C15.378.295.502C16.614.304.502C18.452.132.480C20.306.502C23.550.429.750
    NoteA term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
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Number of the records: 1  

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