Number of the records: 1
proinzulín
Record number d011384 Date 06.06.2025 Type M Topical term proinzulín See also (Later heading) inzulín
UDC D06.472.699.587.200.500D12.644.548.586.200.500D12.776.811.706 Note A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts. 
subject heading
Number of the records: 1