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metylázy modifikujúce DNA

  1. Record numberd015254
    Date06.06.2025
    TypeM - MESH
    Topical termmetylázy modifikujúce DNA
    Other termEnglish (Pseudonym) DNA Modification Methyltransferases
    English (Pseudonym) Modification Methylases
    Slovak (Pseudonym) metylázy modifikačné
    UDCD08.811.150.240D08.811.913.555.500.350
    NoteEnzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.
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