Number of the records: 1  

myši SCID

  1. Record numberd016513
    Date06.06.2025
    TypeM - MESH
    Topical termmyši SCID
    Other termEnglish (Pseudonym) SCID-hu Mice
    English (Pseudonym) SCID Mice
    English (Pseudonym) Severe Combined Immunodeficient Mice
    Slovak (Pseudonym) myši, SCID mutanty
    Slovak (Pseudonym) myši SCID-hu
    Slovak (Pseudonym) myši s ťažkou kombinovanou imunodeficienciou
    UDCB01.050.150.900.649.313.992.635.505.500.550.780
    NoteMice homozygous for the mutant autosomal recessive gene scid which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
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Number of the records: 1  

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