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neoplázia endokrinná mnohopočetná, typ 2a
Record number d018813 Date 06.06.2025 Type M - MESH Topical term neoplázia endokrinná mnohopočetná, typ 2a Other term English (Pseudonym) MEN 2
English (Pseudonym) MEN 2a
English (Pseudonym) Neoplasia, Multiple Endocrine Type 2a
English (Pseudonym) Neoplasms, Multiple Endocrine Type 2a
English (Pseudonym) Sipple Syndrome
Slovak (Pseudonym) MEN2a
Slovak (Pseudonym) MEN 2
Slovak (Pseudonym) MEN 2a
Slovak (Pseudonym) nádory endokrinné mnohopočetné, typ 2a
Slovak (Pseudonym) Sippleov syndróm
See also (Later heading) feochromocytóm
(Later heading) karcinóm medulárny
UDC C04.588.322.400.505C04.651.600.505C04.700.630.505C16.320.700.630.505C19.344.400.505 Note A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (CARCINOMA, MEDULLARY) of the THYROID GLAND, and usually with the co-occurrence of PHEOCHROMOCYTOMA, producing CALCITONIN and ADRENALINE, respectively. Less frequently, it can occur with hyperplasia or adenoma of the PARATHYROID GLANDS. This disease is due to gain-of-function mutations of the MEN2 gene on CHROMOSOME 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a RECEPTOR PROTEIN-TYROSINE KINASE. It is an autosomal dominant inherited disease. 
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Number of the records: 1