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sirtuíny

  1. Record numberd037761
    Date06.06.2025
    TypeM - MESH
    Topical termsirtuíny
    Other termEnglish (Pseudonym) Sir2-like Proteins
    English (Pseudonym) SIRT
    English (Pseudonym) Sirtuin
    Slovak (Pseudonym) SIRT
    Slovak (Pseudonym) SIRTs
    Slovak (Pseudonym) proteíny podobné Sir2 proteínom
    Slovak (Pseudonym) Sir2-podobné proteíny
    Slovak (Pseudonym) sirtuín
    See also(Skutočné meno) proteíny regulačné, pre tichú informáciu, Saccharomyces cerevisiae
    (Later heading) proteíny regulačné, pre tichú informáciu, Saccharomyces cerevisiae
    UDCD08.811.277.087.520.200.650D08.811.913.400.725.115.961D12.776.476.900
    NoteA homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.
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