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metyl-CpG-väzobná doména

  1. Subject h.metyl-CpG-väzobná doména
    Subject h.Methyl CpG Binding Domain
    Entry termsmetyl-CpG DNA väzbová doména
    Scope note in EnglishA protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS.
    See also reference (FX) in Slovak metylácia DNA
    See also reference (FX) in English DNA Methylation
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