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beclin-1

  1. Subject h.beclin-1
    Subject h.Beclin-1
    Entry termsbeclin-1 proteín
    ATG-6 proteín
    GT197 proteín
    dvojito vinutý myozínu podobný proteín interagujúci s Bcl2
    Scope note in EnglishAn autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.
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