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anhydráza karbonická IX

  1. Subject h.anhydráza karbonická IX
    Subject h.Carbonic Anhydrase IX
    Entry termsCAIX proteín
    karboanhydráza 9
    uhličitanová dehydratáza IX
    anhydráza kyseliny uhličitej 9
    karbonátdehydratáza IX
    Scope note in EnglishA carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.
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