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cytochróm P-450 CYP2J2

  1. Subject h.cytochróm P-450 CYP2J2
    Subject h.Cytochrome P-450 CYP2J2
    Entry termsarachidonát epoxidáza
    epoxidáza kyseliny arachidonovej
    cytochróm P-450 arachidonát oxygenáza
    cytochróm P-450 epoxygenáza
    epoxidáza kyseliny arachidonovej, NADPH-dependentná
    CYP2J2
    English X referencesArachidonate Epoxygenase
    Arachidonic Acid Epoxygenase
    Cytochrome P-450 Arachidonate Oxygenase
    Cytochrome P-450 Epoxygenase
    NADPH-Dependent Arachidonic Acid Epoxygenase
    Scope note in EnglishA cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.
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