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Chédiakov-Higashiho syndróm

  1. Subject h.Chédiakov-Higashiho syndróm
    Subject h.Chediak-Higashi Syndrome
    Scope note in EnglishA form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.
    See also reference (FX) in Slovak choroba noriek, aleutská
    See also reference (FX) in English Aleutian Mink Disease
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    (2) - MeSH descriptor
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Number of the records: 1  

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