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ivermektín

  1. Subject h.ivermektín
    Subject h.Ivermectin
    Scope note in EnglishA mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
    Pharmacology effect antiparazitiká
    insekticídy
    Pharmacology effect Antiparasitic Agents
    Insecticides
    Links (26) - ARTICLES
    (1) - CiBaMed
    (5) - BOOKS
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Number of the records: 1  

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