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bunky obrovské

  1. Subject h.bunky obrovské
    Subject h.Giant Cells
    Entry termsbunky gigantické
    syncýcium
    English X referencesGiant Cells, Multinucleated
    Multinucleated Giant Cells
    Polykaryocytes
    Syncytium
    Scope note in EnglishMultinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
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    (1) - MeSH descriptor
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Number of the records: 1  

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