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myši SCID

  1. Subject h.myši SCID
    Subject h.Mice, SCID
    Entry termsmyši, SCID mutanty
    myši SCID-hu
    myši s ťažkou kombinovanou imunodeficienciou
    English X referencesSCID Mice
    SCID-hu Mice
    Severe Combined Immunodeficient Mice
    Scope note in EnglishMice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
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    (2) - BOOKS
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Number of the records: 1  

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