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antigén B7-1

Subject h.	antigén B7-1
Subject h.	B7-1 Antigen
Entry terms	antigény CD80 CD80 antigén antigén aktivačný B-bunkový B7-1 kostimulačná molekula molekula B7-1, kostimulačná B7-1 ligand
English X references	Antigens, CD80 B-Cell Activation Antigen B7-1 Costimulatory Molecule CD80 Antigens
Scope note in English	A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
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Number of the records: 1