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antigény CD40

  1. Subject h.antigény CD40
    Subject h.CD40 Antigens
    Entry termsveľkorodina receptorov pre faktor nekrotizujúci nádory, člen 5
    superrodina receptorov pre faktor nekrotizujúci nádory, člen 5
    CD40 antigén
    CDw40 antigén
    TNFRSF5 receptor
    English X referencesAntigens, CD40
    Tumor Necrosis Factor Receptor Superfamily, Member 5
    Scope note in EnglishMembers of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
    See also reference (FX) in Slovak ligand CD40
    See also reference (FX) in English CD40 Ligand
    Links (4) - ARTICLES
    (1) - MeSH descriptor
    (1) - CiBaMed
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