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degenerácia mozočka, paraneoplastická

  1. Subject h.degenerácia mozočka, paraneoplastická
    Subject h.Paraneoplastic Cerebellar Degeneration
    Entry termsdegenerácia cerebelárna paraneoplastická
    degenerácia cerebelárna paraneoplastická, spojená s anti-Yo
    degenerácia cerebelárna paraneoplastická, anti-Yo asociovaná
    English X referencesCerebellar Degeneration, Paraneoplastic
    Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
    Scope note in EnglishCerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
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