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gény BRCA2

  1. Subject h.gény BRCA2
    Subject h.Genes, BRCA2
    Entry termsBRCA2 gén
    English X referencesBRCA2 Gene
    Scope note in EnglishA tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)
    See also reference (FX) in Slovak BRCA2 proteín
    See also reference (FX) in English BRCA2 Protein
    Links (37) - ARTICLES
    (1) - MeSH descriptor
    (8) - CiBaMed
    (6) - BOOKS
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