A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
Pharmacology effect
cytotoxíny
Pharmacology effect
Cytotoxins
subject heading
openseadragon
Number of the records: 1
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