odpoveď na nesprávne upravené proteíny odpoveď na neusporiadanú formu proteínov
Scope note in English
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.
See also reference (FX) in Slovak
stres endoplazmatického retikula degradácia proteínov spojená s endoplazmatickým retikulom
