Number of the records: 1  

amilorid

  1. Record numberd000584
    Date06.06.2025
    TypeM - MESH
    Topical termamilorid
    See also(Skutočné meno) diuretiká
    (Skutočné meno) blokátory iónových kanálov citlivých na kyslosť
    (Skutočné meno) blokátory epitelových sodíkových kanálov
    UDCD03.383.679.149
    NoteA pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
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Number of the records: 1  

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