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amilorid
Record number d000584 Date 06.06.2025 Type M - MESH Topical term amilorid See also (Skutočné meno) diuretiká
(Skutočné meno) blokátory iónových kanálov citlivých na kyslosť
(Skutočné meno) blokátory epitelových sodíkových kanálov
UDC D03.383.679.149 Note A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) subject heading
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