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botulotoxíny

  1. Record numberd001905
    Date06.06.2025
    TypeM
    Topical termbotulotoxíny
    Other termEnglish (Pseudonym) Botulin
    English (Pseudonym) Botulinum Neurotoxin
    English (Pseudonym) Botulinum Neurotoxins
    English (Pseudonym) Clostridium botulinum Toxins
    Slovak (Pseudonym) botulín
    Slovak (Pseudonym) botulotoxíny klostrídiové
    Slovak (Pseudonym) neurotoxín Botulinum
    Slovak (Pseudonym) neurotoxíny botulínové
    Slovak (Pseudonym) toxíny Clostridium botulinum
    See also(Skutočné meno) neurotoxíny
    (Skutočné meno) inhibítory uvoľňovania acetylcholínu
    (Skutočné meno) botulizmus
    (Later heading) botulizmus
    (Later heading) Clostridium botulinum
    (Later heading) látky cholínergické
    UDCD08.811.277.656.300.480.153D08.811.277.656.675.374.153D12.776.097.156D23.946.123.179
    NoteToxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
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Number of the records: 1  

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