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leukoencefalopatia progresívna multifokálna

  1. Record numberd007968
    Date06.06.2025
    TypeM - MESH
    Topical termleukoencefalopatia progresívna multifokálna
    Other termEnglish (Pseudonym) Encephalitis, JC Polyomavirus
    English (Pseudonym) Progressive Multifocal Leukoencephalopathy
    Slovak (Pseudonym) encefalitída spôsobená JC polyomavírusom
    Slovak (Pseudonym) encefalitída vyvolaná JC polyomavírusom
    UDCC01.207.245.340.500C01.207.399.750.500C01.925.182.525.500C01.925.256.721.500C01.925.839.550C10.228.140.430.520.750.500C10.228.140.695.750C10.228.228.245.340.500C10.228.228.399.750.500C10.314.450C10.586.250.520.750.500
    NoteAn opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
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