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Perifosine downregulates MDR1 gene expression and reverses multidrug-resistant phenotype by inhibiting PI3K/Akt/NF-κB signaling pathway in a human breast cancer cell line

  1. Perifosine downregulates MDR1 gene expression and reverses multidrug-resistant phenotype by inhibiting PI3K/Akt/NF-κB signaling pathway in a human breast cancer cell line / X. Lin ... [et al.]. -- ilustr., obr., grafy, tab. -- Bibliogr. odkazy - Res. angl.

    In Neoplasma : journal of experimental and clinical oncology. -- Bratislava : AEPress, 2012. -- s. 237-354. -- ISSN 0028-2685. -- Vol. 59, no. 3 (2012), s. 248-256

    1. nádory prsníka - farmakoterapia - genetika 2. línia bunková nádorová - patológia - účinky liekov 3. inhibítory proteínkináz 4. rezistencia lieková mnohopočetná - účinky liekov 5. ATP-viažuci kazetový transportér, podrodina B, člen 1 - genetika 6. regulácia expresie génu - účinky liekov 7. NF-kapa B 8. apoptóza - účinky liekov

    I. Lin, X.
    II. Zhang, X.-F.
    III. Wang, Q.
    IV. Li, Jianfeng
    V. Zhang, P.
    VI. Zhao, M.
    VII. Li, X.
    VIII. Neoplasma : journal of experimental and clinical oncology. -- Vol. 59, no. 3 (2012), s. 248-256

    perifosín
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