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C2 domény
Subject h. C2 domény Subject h. C2 Domains Entry terms C2 doména
C2 doména tenzínového typuScope note in English Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE. 
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