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homológ 1 MutL proteínu

  1. Subject h.homológ 1 MutL proteínu
    Subject h.MutL Protein Homolog 1
    Entry termsMutL homológ 1
    COCA2 proteín
    proteín 2 nepolypóznej formy rakoviny hrubého čreva
    MLH1 proteín
    Scope note in EnglishEukaryotic homolog of the bacterial MutL DNA MISMATCH REPAIR protein. It heterodimerizes with MISMATCH REPAIR ENDONUCLEASE PMS2 to form MutL alpha, which is recruited to DNA mismatch sites by the MUTS DNA MISMATCH-BINDING PROTEIN. Mutations in the human MLH1 gene are associated with COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS.
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