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ADAMTS13 proteín

  1. Subject h.ADAMTS13 proteín
    Subject h.ADAMTS13 Protein
    Entry termsdisintegrín a metaloproteináza s proteínom s trombospondínovými motívmi 13
    ADAMTS-13 proteín
    ADAMTS13 proteáza
    proteáza štiepiaca vWF
    proteináza štiepiaca von Willebrandov faktor
    Scope note in EnglishAn ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in the ADAMTS13 gene have been identified in familial cases of PURPURA, THROMBOTIC THROMBOCYTOPENIC and defects in ADAMTS13 activity are associated with MYOCARDIAL INFARCTION; BRAIN ISCHEMIA; PRE-ECLAMPSIA; and MALARIA.
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