Number of the records: 1
serín/treonín kináza-2 bohatá na leucínové repetície
Subject h. serín/treonín kináza-2 bohatá na leucínové repetície Subject h. Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Entry terms serín/treonín kináza-2 s repetíciami bohatými na leucín
dardarín proteín
LRRK2 proteín
PARK8 proteínScope note in English A serine/threonine protein kinase with GTPase activity that contains 12 LEUCINE-rich repeats in its central region and 7 WD repeats C-terminal to its kinase and GTPase domains. It localizes to TRANSPORT VESICLES; the OUTER MITOCHONDRIAL MEMBRANE; and the GOLGI APPARATUS. It functions in PROTEIN TRANSPORT; regulates neuron morphology in the central nervous system, and also functions in the trafficking of SYNAPTIC VESICLES. Mutations in the LRRK2 gene have been identified in autosomal dominant cases of PARKINSON DISEASE (PARK8). 
subject heading
Number of the records: 1