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homológ proteínu-1 súvisiaceho s autofágiou
Subject h. homológ proteínu-1 súvisiaceho s autofágiou Subject h. Autophagy-Related Protein-1 Homolog Entry terms homológ proteínu-1 spojeného s autofágiou
serín/treonín proteínkináza ULK1
ULK1 proteín
Unc-51-podobná kináza 1Scope note in English A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates. 
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