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proteín 7 súvisiaci s autofágiou
Subject h. proteín 7 súvisiaci s autofágiou Subject h. Autophagy-Related Protein 7 Entry terms proteín 7 spojený s autofágiou
ATG12-aktivujúci enzým E1 ATG7
ATG7 proteín
proteín podobný enzýmu E1 aktivujúcemu ubikvitínScope note in English An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition. 
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