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koaktivátor 1-alfa receptora aktivovaného peroxizómovými proliferátormi gama

  1. Subject h.koaktivátor 1-alfa receptora aktivovaného peroxizómovými proliferátormi gama
    Subject h.Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
    Entry termskoaktivátor 1-alfa receptora aktivovaného proliferátormi peroxizómov gama
    PGC-1-alfa proteín
    PPARGC-1-alfa proteín
    PPARGC1a proteín
    Scope note in EnglishA transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.
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