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APOBEC-3G deamináza
Subject h. APOBEC-3G deamináza Subject h. APOBEC-3G Deaminase Entry terms APOBEC-3G proteín
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APOBEC3G deamináza
CEM15 proteínScope note in English An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS. subject heading
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