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proteín 1 supresorový nádorový, viažuci sa na p-53
Subject h. proteín 1 supresorový nádorový, viažuci sa na p-53 Subject h. Tumor Suppressor p53-Binding Protein 1 Entry terms 53BP1 proteín
TP53BP1 proteín
p202 proteínScope note in English A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation. 
subject heading
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