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peptidyl-prolyl izomeráza NIMA-interagujúca

  1. Subject h.peptidyl-prolyl izomeráza NIMA-interagujúca
    Subject h.NIMA-Interacting Peptidylprolyl Isomerase
    Entry termsPIN1 proteín
    peptidyl-prolyl cis-trans izomeráza Pin1
    Pin1 peptidyl-prolyl izomeráza
    Scope note in EnglishA highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1.
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Number of the records: 1  

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