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prsty zinkové, PHD

  1. Subject h.prsty zinkové, PHD
    Subject h.PHD Zinc Fingers
    Entry termsPHD domény
    domény zinkových prstov
    PHD prsty
    PHD motív
    PHD zinkový prst
    Scope note in EnglishZinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.
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