Number of the records: 1  

DNA 5-cytozín metyltransferáza 1

  1. SYSd000076123
    LBL
      
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    $a 20180101asloy0103 ba0
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    $a DNA 5-cytozín metyltransferáza 1 $x AD $x AE $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x DF $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo
    300
    1-
    $a 2018 (1999) $8 eng
    330
    1-
    $a A DNA (cytosine-5-)-methyltransferase that contains a central CxxC type zinc finger motif. It binds poly(ADP)-ribose and its expression is regulated by POLY (ADP-RIBOSE) POLYMERASE-1. DNMT1 methylates CpG residues, with a preference for hemimethylated DNA, and associates with DNA replication sites in S PHASE to maintain the methylation pattern in the newly synthesized strand, which is essential for EPIGENETIC PROCESSES. It also associates with CHROMATIN during G2 PHASE and MITOSIS to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development; mutations in the DNMT1 gene are associated with HEREDITARY SENSORY NEUROPATHY TYPE 1 class E. $8 eng
    450
      
    $a DNA (cytozín-5-)-metyltransferáza 1 $5 e $8 slo
    450
      
    $a DNMT1 enzým $5 e $8 slo
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    $3 sllk_un_auth*d016335 $Y Zinc Fingers $5 F $a motívy zinkových prstov
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    $a D12.776.157.687.313
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    $a D12.776.660.720.313
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    $a DNA (Cytosine-5-)-Methyltransferase 1 $8 eng
    801
    -0
    $a SK $b BA006 $c 20180615
    801
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    $a SK $b BA006 $c 20180713
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    $x M
Number of the records: 1  

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