Number of the records: 1
DNA 5-cytozín metyltransferáza 1
SYS d000076123 LBL 00000nx^^^2200181-^^45^^ 005 20240119200809.9 100 $a 20180101asloy0103 ba0 152 $b mesh 250 $a DNA 5-cytozín metyltransferáza 1 $x AD $x AE $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x DF $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo 300 1-
$a 2018 (1999) $8 eng 330 1-
$a A DNA (cytosine-5-)-methyltransferase that contains a central CxxC type zinc finger motif. It binds poly(ADP)-ribose and its expression is regulated by POLY (ADP-RIBOSE) POLYMERASE-1. DNMT1 methylates CpG residues, with a preference for hemimethylated DNA, and associates with DNA replication sites in S PHASE to maintain the methylation pattern in the newly synthesized strand, which is essential for EPIGENETIC PROCESSES. It also associates with CHROMATIN during G2 PHASE and MITOSIS to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development; mutations in the DNMT1 gene are associated with HEREDITARY SENSORY NEUROPATHY TYPE 1 class E. $8 eng 450 $a DNA (cytozín-5-)-metyltransferáza 1 $5 e $8 slo 450 $a DNMT1 enzým $5 e $8 slo 550 $3 sllk_un_auth*d016335 $Y Zinc Fingers $5 F $a motívy zinkových prstov 686 $a D08.811.913.555.500.350.100.500.500 686 $a D12.776.157.687.313 686 $a D12.776.660.720.313 750 $a DNA (Cytosine-5-)-Methyltransferase 1 $8 eng 801 -0
$a SK $b BA006 $c 20180615 801 -2
$a SK $b BA006 $c 20180713 980 $x M
Number of the records: 1