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cieľ rapamycínového komplexu 1, mechanistický
Subject h. cieľ rapamycínového komplexu 1, mechanistický Subject h. Mechanistic Target of Rapamycin Complex 1 Entry terms TOR komplex 1
TORC1
cieľ rapamycínového komplexu 1
mTORC1 komplex
mTORC1Scope note in English An evolutionarily conserved multiprotein complex that functions as a cellular energy sensor and regulator of protein synthesis for cell growth and proliferation. It consists of TOR SERINE-THREONINE KINASES; REGULATORY-ASSOCIATED PROTEIN OF MTOR (RAPTOR); MLST8 PROTEIN; and AKT1 substrate 1 protein. The activity of the complex is regulated by SIROLIMUS; INSULIN; GROWTH FACTORS; PHOSPHATIDIC ACIDS; some amino acids or amino acid derivatives, and OXIDATIVE STRESS. 
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