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CCCTC-viažuci faktor
Subject h. CCCTC-viažuci faktor Subject h. CCCTC-Binding Factor Entry terms CTCF proteín
DNA-viažuci proteín CTCFScope note in English A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING. 
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