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proteín centromérový, typ A

  1. Subject h.proteín centromérový, typ A
    Subject h.Centromere Protein A
    Entry termsproteín centromérový typu A
    CENP-A proteín
    CENPA proteín
    autoantigény centromérové 17K
    proteín centromérový 17K
    Scope note in EnglishA 17 kDa, centromeric, poly(ADP)-ribose binding protein that is structurally similar to HISTONE H3 and localizes to NUCLEOSOMES within the CENTROMERE; specifically within the region that binds KINETOCHORES, where it replaces histone H3. It plays a critical role in recruiting kinetochore proteins and progression through MITOSIS, chromosome segregation, and CYTOKINESIS. It also binds sera from patients with some scleroderma-like AUTOIMMUNE DISEASES.
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Number of the records: 1  

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