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tyrozínkináza pri agamaglobulinémii

  1. Subject h.tyrozínkináza pri agamaglobulinémii
    Subject h.Agammaglobulinaemia Tyrosine Kinase
    Entry termsBrutonova tyrozínkináza
    tyrozínkináza špecifická pre progenitory B-buniek
    BTK kináza
    Scope note in EnglishA non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.
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