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trabektedín
Subject h. trabektedín Subject h. Trabectedin Entry terms Ecteinascidin 743
YondelisScope note in English A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy. 
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